Houston Astros at Cleveland Guardians, Apr 21, 2026

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Houston Astros at Cleveland Guardians — Apr 21, 2026

MLB game 824448: Houston Astros at Cleveland Guardians at Progressive Field on Apr 21, 2026. Cleveland Guardians beat Houston Astros 8-5. Probable starters: Ryan Weiss (Houston Astros) and Parker Messick (Cleveland Guardians). 11 pitchers have appeared or are expected; each name below links to a full netpitch pitcher profile.

Houston Astros pitchers
PitcherPitchesInnings
Ryan Weiss861–4
Colton Gordon174–5
Kai-Wei Teng315–7
Bryan King158
Enyel De Los Santos158
Cleveland Guardians pitchers
PitcherPitchesInnings
Parker Messick851–5
Shawn Armstrong116
Tim Herrin167
Connor Brogdon117
Peyton Pallette218
Cade Smith189